(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine

(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine - Names and Identifiers

Name	(R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE
Synonyms	R-MBT-PEM (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE (R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHANAMINE (R)-1-[BIS-3,5-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-amine Benzenemethanamine, a-methyl-3,5-bis(trifluoromethyl)-,(aR)- Benzenemethanamine, α-methyl-3,5-bis(trifluoromethyl)-, (αR)- Benzenemethanamine, a-methyl-3,5-bis(trifluoromethyl)-, hydrochloride, (aR)- (9CI)
CAS	127733-47-5
InChI	InChI=1/C10H9F6N/c1-5(17)6-2-7(9(11,12)13)4-8(3-6)10(14,15)16/h2-5H,17H2,1H3/t5-/m1/s1

(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine - Physico-chemical Properties

Molecular Formula	C10H9F6N
Molar Mass	257.18
Density	1.327g/cm³
Boling Point	168.9°C at 760 mmHg
Flash Point	66.3°C
Vapor Presure	1.59mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.422

(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Note	Irritant

(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine - Introduction

(R)-1-[3,5-bis (trifluoromethyl) phenyl] ethylamine is an organic compound having the formula C10H11F6N. The following is a description of its nature, use, preparation and safety information:

1. nature:
(R)-1-[3,5-bis (trifluoromethyl) phenyl] ethylamine is a solid compound soluble in organic solvents. It has the characteristics of a trifluoromethyl substituent, which makes its chemical properties different from similar compounds to a certain extent.

2. use:
This compound is mainly used as a catalyst in organic synthesis reactions. It can be used as a stereoselective reagent in hydrogenation and reduction reactions, and can catalyze the stereoselective synthesis of important organic molecules.

3. Preparation method:
The preparation method of (R)-1-[3,5-bis (trifluoromethyl) phenyl] ethylamine is relatively complex and generally requires technical support from organic synthesis. The preparation steps include the reaction of trifluoromethylbenzaldehyde with acetonitrile, reduction reaction and resolution reaction.

4. Safety Information:
The safety information of (R)-1-[3,5-bis (trifluoromethyl) phenyl] ethylamine is rarely reported, but due to its fluorine-based and chemical reaction characteristics, protective measures should be paid attention to when using. During use, it is recommended to wear protective gloves, goggles and protective mask, and maintain good ventilation conditions. In addition, avoid contact with skin, eyes and mucous membranes, and avoid inhalation or ingestion. In case of accident, seek medical help immediately.

Please note that this information is partially derived from published literature research, but specific laboratory operations and safety operations should be carried out according to specific research conditions and requirements. Before use, it is necessary to understand the relevant material safety data sheets and research literature in detail, and operate under the guidance of professionals.

Last Update：2024-04-10 22:29:15